منابع مشابه
Primary structure of human pepsinogen gene.
A recombinant clone, which covers the pepsinogen gene in a single insert, has been isolated by screening a library of human genomic DNA, using a swine pepsinogen cDNA as a probe. Sequence analysis of coding DNA segments of the clone revealed that the pepsinogen gene occupies approximately 9.4-kilobase pairs of the genomic DNA and is separated into nine exons by eight introns of various lengths....
متن کاملRadioimmunoassay of human pepsinogen A and pepsinogen C.
We describe the development of radioimmunoassays to measure both human pepsinogen A and pepsinogen C concentrations in serum. The antibodies were raised in goats by immunization with purified pepsinogen A or C. The affinity constants of the respective antibodies were 20.10(10) l/mol and 7.10(10) l/mol. Pepsinogens A and C were labeled with Na 125I by the chloramine T method. The binding between...
متن کاملCrystal Structure of Human Liver
AKR1D1 (steroid 5 -reductase) reduces all 4-3-ketosteroids to form 5 -dihydrosteroids, a first step in the clearance of steroid hormonesandanessential step in thesynthesisofallbileacids.The reduction of the carbon–carbon double bond in an , -unsaturated ketone by 5 -reductase is a unique reaction in steroid enzymology because hydride transfer from NADPH to the -face of a 4-3-ketosteroid yields ...
متن کاملCrystal structure of human fibrinogen.
A crystal structure of human fibrinogen has been determined at approximately 3.3 A resolution. The protein was purified from human blood plasma, first by a cold ethanol precipitation procedure and then by stepwise chromatography on DEAE-cellulose. A product was obtained that was homogeneous on SDS-polyacrylamide gels. Nonetheless, when individual crystals used for X-ray diffraction were examine...
متن کاملCrystal structure of human transgelin.
Transgelin (TAGLN), also known as smooth muscle protein 22 (SM22), is a highly conserved protein found in smooth muscle tissues of adult vertebrates. Abolition of transgelin gene expression by the oncogenic Ras may be an important early event in tumor progression and a diagnostic marker for breast and colon cancer development. Transgelin contains a single calponin homology (CH) domain. However,...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 1996
ISSN: 0108-7673
DOI: 10.1107/s0108767396094937